Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | TNF | P01375 | 3/20 | 0.47 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12118786 | 0.97 | MDM4 (0.48) | MDM4TP53TNFSLC17A5TLR2 | |
| SCHEMBL21838223 | 0.97 | MDM4 (0.48) | MDM4TP53TNFSLC17A5TLR2 | |
| SCHEMBL29477061 | 0.97 | MDM4 (0.48) | MDM4TP53TNFSLC17A5TLR2 | |
| SCHEMBL30889963 | 0.97 | MDM4 (0.48) | MDM4TP53TNFSLC17A5TLR2 | |
| SCHEMBL21838225 | 0.97 | MDM4 (0.48) | MDM4TP53TNFSLC17A5TLR2 | |
| SCHEMBL21837915 | 0.89 | TLR2 (0.49) | MDM4TP53TNFSLC17A5TLR2 | |
| SCHEMBL21837912 | 0.89 | TLR2 (0.49) | MDM4TP53TNFSLC17A5TLR2 | |
| SCHEMBL22092029 | 0.88 | TLR2 (0.51) | MDM4TP53TNFTLR2MDM2 | |
| SCHEMBL22092027 | 0.88 | TLR2 (0.51) | MDM4TP53TNFTLR2MDM2 | |
| SCHEMBL25657764 | 0.87 | TLR2 (0.49) | MDM4TP53TNFSLC17A5TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099864-A1 | PREPARATION OF ORGANOPHOSPHATE PEPTIDE ADDUCTS | BATTELLE MEMORIAL INSTITUTE | 2015-04-09 | — | — | US | disclosed |