Guretolimod

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Guretolimod SCHEMBL15392137	1.00	TLR7 (1.00)	TLR7TLR8
	SCHEMBL29447484	0.93	TLR7 (0.87)	TLR7TLR8
	SCHEMBL16624340	0.93	TLR7 (0.87)	TLR7TLR8
	SCHEMBL20936318	0.93	TLR7 (0.87)	TLR7TLR8
	SCHEMBL15393115	0.92	TLR7 (1.00)	TLR7TLR8
	SCHEMBL15393191	0.92	TLR7 (1.00)	TLR7TLR8
	SCHEMBL16617093	0.92	TLR7 (0.85)	TLR7TLR8
	SCHEMBL29811247	0.92	TLR7 (0.85)	TLR7TLR8
	SCHEMBL16617095	0.92	TLR7 (0.85)	TLR7TLR8
	SCHEMBL16624385	0.91	TLR7 (0.84)	TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.