Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6095818 | 1.00 | CA1 (1.00) | — | |
| Bromide SCHEMBL1872791 | 1.00 | — | — | |
| Bromide SCHEMBL597803 | 1.00 | — | — | |
| Bromide SCHEMBL8358501 | 1.00 | — | — | |
| Bromide SCHEMBL1061497 | 1.00 | — | — | |
| Bromide SCHEMBL22734108 | 1.00 | — | — | |
| Bromide SCHEMBL57402 | 1.00 | — | — | |
| Bromide SCHEMBL41784 | 1.00 | — | — | |
| Bromide SCHEMBL183 | 1.00 | — | — | |
| Bromide SCHEMBL29362293 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 16643 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260027105-A1 | COMPOUND MEDICINE COMPOSITION FOR TREATING GLAUCOMA AND USE OF SAME | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2026-01-29 | — | — | US | claimed |
| US-20260027084-A1 | TREATMENT OF MULTIPLE MYELOMA | SPRINGWORKS THERAPEUTICS INC (US) | 2026-01-29 | — | — | US | claimed |
| EP-4678635-A1 | CRYSTAL FORM OF NIROGACESTAT DIHYDROBROMATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Crystal Pharmaceutical (Suzhou) Co., Ltd. (CN) | 2026-01-14 | — | — | EP | claimed |
| US-20260000648-A1 | TREATMENT OF OVARIAN CANCER WITH NIROGACESTAT | SPRINGWORKS THERAPEUTICS INC (US) | 2026-01-01 | — | — | US | claimed |
| EP-4646419-A1 | METHOD FOR PREPARING A NEODYMIUM ALKYL PHOSPHATE SOLUTION | Umicore Speciality Materials Brugge NV (BE) | 2025-11-12 | — | — | EP | claimed |
| EP-4561572-A1 | TREATMENT OF MULTIPLE MYELOMA | Springworks Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | claimed |
| CN-113054529-B | Optical communication O-band silicon-based high-speed semiconductor laser chip and manufacturing method thereof | 福建中科光芯光电科技有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-113169094-B | Vacuum pump protection to avoid deposition byproduct accumulation | 朗姆研究公司 | 2025-05-09 | — | — | CN | claimed |
| CN-115947682-B | Synthesis method of 3-bromo-2-hydroxy-6-methylpyridine | 山西永津集团有限公司 | 2025-04-18 | — | — | CN | claimed |
| WO-2025077920-A1 | PREPARATION METHOD AND APPLICATION OF A CHIRAL AMINE COMPOUND AND ITS SALTS | TONGLI BIOMEDICAL CO., LTD. (CN) | 2025-04-17 | — | — | WO | claimed |
| US-RE29668-E | 4-OXO-1,2-BENZOTHIAZINE-3-CARBOXAMIDE, 1,1-DIOXIDES, ANTIINFLAMMATORY | PFIZER INC. (US) | 1978-06-13 | — | — | US | claimed |
| US-4072664-A | TEREPHTHALIC ACID, P-PHENYLENEDIAMINE; FILAMENTS | TOYOBO CO., LTD. (JA) | 1978-02-07 | — | — | US | claimed |
| US-4072809-A | ALKYLALUMINUM-TITANIUM CHLORIDE, HYDROGEN SULFIDE AND AMINE, AMINE OXIDE OR PHOSPHITE | STANDARD OIL COMPANY (INDIANA) (US) | 1978-02-07 | — | — | US | claimed |
| US-4042542-A | Process for removing polymer from reaction mixture | STAUFFER CHEMICAL COMPANY (US) | 1977-08-16 | — | — | US | claimed |
| US-4042571-A | Fire-retardant polyamides from naphthalene dicarboxylic reactant and halogenated carboxylic reactant | TEIJIN LIMITED (JA) | 1977-08-16 | — | — | US | claimed |
| US-4028333-A | POLYOLEFINS | VELSICOL CHEMICAL CORPORATION (US) | 1977-06-07 | — | — | US | claimed |
| US-4028091-A | BIPYRIDYLIUM SALTS AND A THIOCARBAMATE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) | 1977-06-07 | — | — | US | claimed |
| US-4027003-A | MULTISTEP | ORGANIZATION CONTROL SERVICES, INC. (US) | 1977-05-31 | — | — | US | claimed |
| US-4024092-A | Polymer compositions containing stilbene halide additives | FOSTER GRANT CO., INC. (US) | 1977-05-17 | — | — | US | claimed |
| US-3954576-A | Electrolytic process for preparing tetravalent alkyltin halide compositions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-05-04 | — | — | US | claimed |