Glycerylphosphate

Glycerylphosphate

SCHEMBL16618492

C[N+](C)(C)CCO.O=P(O)(O)OC(CO)CO

nearest known ligand 0.46

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Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2

The experimentally established mechanism targets of Glycerylphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP3A4 P08684 1/20 0.44
SLC5A7 Q9GZV3 1/20 0.44
BBOX1 O75936 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PTPN1 P18031 1/20 0.32
SMPD1 P17405 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerylphosphate SCHEMBL59773 0.81 SMPD1 (0.37) PTPN1SMPD1
Choline SCHEMBL16267506 0.81 MEN1 (0.32) MEN1LMNAKMT2ACYP3A4SLC5A7
Glycerylphosphate SCHEMBL2130013 0.79 SMPD1 (0.35) PTPN1SMPD1
Glycerylphosphate SCHEMBL28311028 0.79 SMPD1 (0.35) PTPN1SMPD1
Glycerylphosphate SCHEMBL27579867 0.79 SMPD1 (0.35) PTPN1SMPD1
Glycerylphosphate SCHEMBL9391484 0.79 SMPD1 (0.35) PTPN1SMPD1
Glycerylphosphate SCHEMBL14482182 0.79 SMPD1 (0.35) PTPN1SMPD1
Glycerylphosphate SCHEMBL2487169 0.79 SMPD1 (0.35) PTPN1SMPD1
Glycerylphosphate SCHEMBL28755288 0.79 SMPD1 (0.35) PTPN1SMPD1
Glycerylphosphate SCHEMBL28311177 0.79 SMPD1 (0.35) PTPN1SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020029221-A1 COMPOSITION WITH INHIBITING FAT FORMATION AND ANTIOXIDATIVE ACTIVITIES AND USE THEREOF 黄福星 2020-02-13 WO claimed
WO-2023202099-A1 USE OF GLYCEROPHOSPHORYLCHOLINE IN REGULATING AND CONTROLLING LEVEL AND DISTRIBUTION OF NAD+ IN CELLS 深圳先进技术研究院 2023-10-26 WO disclosed
WO-2020029221-A1 COMPOSITION WITH INHIBITING FAT FORMATION AND ANTIOXIDATIVE ACTIVITIES AND USE THEREOF 黄福星 2020-02-13 WO disclosed
US-20160207879-A1 METHODS AND INDUSTRIAL PROCESSES FOR THE GENERATION OF FREE FATTY ACIDS AND DERIVATIVES THEREOF FROM OIL GUMS INVENTURE RENEWABLES INC (US) 2016-07-21 US disclosed
WO-2015050656-A2 METHODS AND INDUSTRIAL PROCESSES FOR THE GENERATION OF FREE FATTY ACIDS DERIVATIVES THEREOF FROM OIL GUMS INVENTURE RENEWABLES, INC. (US) 2015-04-09 WO disclosed