Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.54 |
| ▸ | BRD2 | P25440 | 4/20 | 0.51 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.51 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619218 | 0.84 | BRD4 (0.47) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16619404 | 0.83 | BRD4 (0.63) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16618873 | 0.82 | BRD4 (0.76) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16618912 | 0.75 | BRD4 (0.77) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16619407 | 0.74 | BRD4 (0.55) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16618811 | 0.74 | BRD4 (0.60) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16619330 | 0.74 | BRD4 (0.60) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16619283 | 0.72 | BRD4 (0.51) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16619653 | 0.72 | BRD4 (0.66) | BRD4BRD2BRD3BRDTCYP3A4 | |
| SCHEMBL16619458 | 0.72 | BRD4 (0.64) | BRD4BRD2BRD3BRDTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | claimed |
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |