Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16213542 | 0.83 | MAPK1 (0.61) | MAPK1CYP3A4 | |
| SCHEMBL16619996 | 0.83 | MAPK1 (0.78) | MAPK1CYP3A4 | |
| SCHEMBL16213534 | 0.82 | MAPK1 (0.69) | MAPK1 | |
| SCHEMBL16619917 | 0.80 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL18024550 | 0.75 | MAPK1 (0.80) | MAPK1 | |
| SCHEMBL18024765 | 0.73 | MAPK1 (0.80) | MAPK1CYP3A4 | |
| SCHEMBL17986627 | 0.73 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL16213348 | 0.72 | MAPK1 (0.58) | MAPK1 | |
| SCHEMBL19223415 | 0.71 | MAPK1 (1.00) | MAPK1CYP3A4 | |
| SCHEMBL16620235 | 0.71 | MAPK1 (1.00) | MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052096-A1 | INHIBITORS OF ERK AND METHODS OF USE | Kura Oncology, Inc. (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015051341-A1 | INHIBITORS OF ERK AND METHODS OF USE | ARAXES PHARMA LLC (US) | 2015-04-09 | — | — | WO | disclosed |