Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619475 | 0.79 | HDAC6 (0.58) | ALBCHEK2HDAC6HDAC3HDAC1 | |
| SCHEMBL16619938 | 0.79 | ALB (0.58) | ALBCHEK2 | |
| SCHEMBL16619766 | 0.74 | ALB (0.67) | ALBCHEK2 | |
| SCHEMBL16630761 | 0.71 | ALB (0.86) | ALBSCDCHEK2HDAC6HDAC3 | |
| SCHEMBL16619144 | 0.71 | ALB (0.61) | ALBSCDCHEK2HDAC6HDAC3 | |
| SCHEMBL16619698 | 0.70 | ALB (0.54) | ALBSCDCHEK2 | |
| SCHEMBL16619335 | 0.69 | ALB (0.62) | ALBHDAC6HDAC3HDAC1HDAC8 | |
| SCHEMBL16630759 | 0.66 | ALB (0.78) | ALBSCDCHEK2HDAC6HDAC3 | |
| SCHEMBL16619809 | 0.66 | ALB (0.71) | ALBSCDCHEK2FLT3 | |
| SCHEMBL20982580 | 0.65 | HDAC6 (0.62) | CHEK2HDAC6HDAC3HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052483-A1 | COMPOUNDS FOR AFFINITY CHROMATOGRAPHY AND FOR EXTENDING THE HALF-LIFE OF A THERAPEUTIC AGENT | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015049651-A1 | COMPOUNDS FOR AFFINITY CHROMATOGRAPHY AND FOR EXTENDING THE HALF-LIFE OF A THERAPEUTIC AGENT | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-04-09 | — | — | WO | disclosed |