⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16620434 | 1.00 | — | — | |
| SCHEMBL16620750 | 0.90 | — | — | |
| SCHEMBL7247702 | 0.88 | GRIN2D (0.30) | — | |
| SCHEMBL7247699 | 0.88 | GRIN2D (0.30) | — | |
| SCHEMBL16620683 | 0.85 | — | — | |
| Iodide SCHEMBL7254660 | 0.83 | — | — | |
| Iodide SCHEMBL7250541 | 0.83 | — | — | |
| SCHEMBL16620706 | 0.83 | — | — | |
| SCHEMBL1032869 | 0.82 | GRIN2D (0.31) | — | |
| SCHEMBL6692702 | 0.81 | NPSR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052134-A2 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | Merck Sharp & Dohme Corp. (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015051052-A2 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2015-04-09 | — | — | WO | disclosed |