SCHEMBL16620412

SCHEMBL16620412

Cc1ccccc1N=CCCCC#N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.45
MAPT P10636 6/20 0.39
ALDH1A1 P00352 5/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
PKM P14618 1/20 0.39
LMNA P02545 3/20 0.39
HPGD P15428 1/20 0.39
KDM4E B2RXH2 4/20 0.36
RECQL P46063 2/20 0.36
POLB P06746 1/20 0.36
MPI P34949 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TDP1 Q9NUW8 2/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
THRB P10828 1/20 0.33
HTT P42858 1/20 0.33
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16620411 1.00 CYP2C9 (0.45) CYP2C9MAPTALDH1A1NPC1RAB9A
SCHEMBL27775481 0.78 CYP2C9 (0.49) CYP2C9MAPTALDH1A1NPC1RAB9A
SCHEMBL17985089 0.76 KMT2A (0.35) CYP2C9MAPTALDH1A1NPC1RAB9A
SCHEMBL17985088 0.76 KMT2A (0.35) CYP2C9MAPTALDH1A1NPC1RAB9A
SCHEMBL1758445 0.75 CYP2C9 (0.53) CYP2C9MAPTALDH1A1NPC1RAB9A
SCHEMBL1758444 0.75 CYP2C9 (0.53) CYP2C9MAPTALDH1A1NPC1RAB9A
SCHEMBL16620373 0.74 CYP2C9 (0.45) CYP2C9MAPTALDH1A1NPC1RAB9A
SCHEMBL16620375 0.74 CYP2C9 (0.45) CYP2C9MAPTALDH1A1NPC1RAB9A
SCHEMBL16620710 0.73 CYP2D6 (0.38) CYP2C9MAPTALDH1A1SMN1; SMN2LMNA
SCHEMBL16620709 0.73 CYP2D6 (0.38) CYP2C9MAPTALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590208-B2 Polymers functionalized with imine compounds containing a cyano group BRIDGESTONE CORPORATION (JP) 2020-03-17 US claimed
EP-3052531-B1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORP (JP) 2024-07-24 EP disclosed
US-11066486-B2 Polymers functionalized with imine compounds containing a cyano group BRIDGESTONE CORPORATION (JP) 2021-07-20 US disclosed
US-20200157253-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORPORATION (JP) 2020-05-21 US disclosed
US-10590208-B2 Polymers functionalized with imine compounds containing a cyano group BRIDGESTONE CORPORATION (JP) 2020-03-17 US disclosed
US-20160237179-A1 Polymers Functionalized With Imine Compounds Containing A Cyano Group BRIDGESTONE CORPORATION (JP) 2016-08-18 US disclosed
EP-3052531-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP Bridgestone Corporation (JP) 2016-08-10 EP disclosed
WO-2015050947-A1 POLYMERS FUNCTIONALIZED WITH IMINE COMPOUNDS CONTAINING A CYANO GROUP BRIDGESTONE CORPORATION (JP) 2015-04-09 WO disclosed