Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887738 | 0.90 | BACE1 (0.52) | BACE1APP | |
| SCHEMBL9948474 | 0.88 | BACE1 (0.52) | BACE1APP | |
| SCHEMBL9948476 | 0.88 | BACE1 (0.52) | BACE1APP | |
| SCHEMBL16622125 | 0.87 | BACE1 (0.40) | BACE1APP | |
| SCHEMBL16622126 | 0.86 | BACE1 (0.39) | BACE1APP | |
| SCHEMBL9948077 | 0.82 | BACE1 (0.52) | BACE1APP | |
| SCHEMBL9948076 | 0.82 | BACE1 (0.52) | BACE1APP | |
| SCHEMBL9948154 | 0.81 | BACE1 (0.52) | BACE1APP | |
| SCHEMBL12746365 | 0.81 | BACE1 (0.52) | BACE1APP | |
| SCHEMBL7893775 | 0.80 | BACE1 (0.47) | BACE1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000185-B2 | Cycloalkyl ether compounds and their use as BACE inhibitors | ASTRAZENECA AB (SE) | 2015-04-07 | — | — | US | disclosed |
| US-9000185-B2 | Cycloalkyl ether compounds and their use as BACE inhibitors | ASTRAZENECA AB (SE) | 2015-04-07 | — | — | US | disclosed |