Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15195463 | 0.78 | HRH3 (0.42) | HRH3CYP2C19 | |
| SCHEMBL21924100 | 0.77 | HRH3 (0.41) | HRH3CYP2C19 | |
| SCHEMBL27983183 | 0.77 | HRH3 (0.41) | HRH3CYP2C19 | |
| SCHEMBL22555722 | 0.77 | TSHR (0.42) | HRH3CYP2C19 | |
| SCHEMBL27983489 | 0.77 | HRH3 (0.41) | HRH3CYP2C19 | |
| SCHEMBL27983184 | 0.77 | HRH3 (0.41) | HRH3CYP2C19 | |
| SCHEMBL20625573 | 0.75 | PPARG (0.40) | CYP2C19 | |
| SCHEMBL8113565 | 0.74 | PTGS1 (0.47) | — | |
| SCHEMBL8122125 | 0.74 | PTGS1 (0.47) | — | |
| SCHEMBL15184685 | 0.74 | HRH3 (0.44) | HRH3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491926-B1 | Treatment of protein degradation disorders | HARVARD COLLEGE (US) | 2018-05-09 | — | — | EP | disclosed |
| US-9572854-B2 | Treatment of protein degradation disorders | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-02-21 | — | — | US | disclosed |
| US-8999289-B2 | Treatment of protein degradation disorders | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-04-07 | — | — | US | disclosed |