Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.61 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14821941 | 0.90 | CTSC (0.62) | CTSCCTSK | |
| SCHEMBL15081686 | 0.89 | CTSC (0.63) | CTSCCTSK | |
| SCHEMBL16622380 | 0.88 | CTSC (0.55) | CTSCCTSK | |
| SCHEMBL14821863 | 0.87 | CTSC (0.66) | CTSCCTSK | |
| SCHEMBL15084123 | 0.87 | CTSC (0.57) | CTSCCTSK | |
| SCHEMBL14821937 | 0.87 | CTSC (0.67) | CTSCCTSK | |
| SCHEMBL15081683 | 0.87 | CTSC (0.56) | CTSCCTSK | |
| SCHEMBL14821864 | 0.87 | CTSC (0.64) | CTSCCTSK | |
| SCHEMBL14821862 | 0.86 | CTSC (0.67) | CTSCCTSK | |
| SCHEMBL14821940 | 0.86 | CTSC (0.67) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999975-B2 | Substituted N- [1-cyano-2- (phenyl) ethyl] -2-azabicyclo [2.2.1] heptane-3-carboxamide inhibitors of cathepsin C | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-07 | — | — | US | disclosed |