SCHEMBL16622425

SCHEMBL16622425

CCCc1cccc(Cn2nc(C)c3c(NC(=O)c4cnc5cc(OCCN6CCN(C)CC6)ccn45)cccc32)n1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9974319 0.95 CSF1R (0.83) CSF1R
SCHEMBL9974323 0.93 CSF1R (0.89) CSF1R
Hydrochloric Acid SCHEMBL15312543 0.92 CSF1R (0.87) CSF1R
SCHEMBL9939188 0.92 CSF1R (0.78) CSF1R
SCHEMBL15318647 0.91 CSF1R (0.75) CSF1R
SCHEMBL15312797 0.91 CSF1R (0.80) CSF1R
SCHEMBL15312587 0.90 CSF1R (0.78) CSF1R
SCHEMBL9941679 0.90 CSF1R (0.80) CSF1R
SCHEMBL15721496 0.89 CSF1R (0.85) CSF1R
SCHEMBL9941843 0.88 CSF1R (0.87) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651939-B1 SUBSTITUTED N-(1H-INDAZOL-4-YL)IMIDAZO[1,2-a]PYRIDINE-3-CARBOXAMIDE COMPOUNDS AS TYPE III RECEPTOR TYROSINE KINASE INHIBITORS ARRAY BIOPHARMA INC (US) 2015-04-08 EP disclosed