Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.76 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | PNLIP | P16233 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15588778 | 1.00 | PTPN1 (0.76) | PTPN1PTPN2POLBMAPTCYP2C9 | |
| SCHEMBL24422153 | 0.86 | PTPN1 (1.00) | PTPN1PTPN2POLBMAPTRPS6KA5 | |
| SCHEMBL30288170 | 0.79 | PTPN1 (0.81) | PTPN1PTPN2POLBMAPTRPS6KA5 | |
| SCHEMBL16622816 | 0.75 | POLB (0.81) | PTPN1PTPN2POLBMAPTCYP2C9 | |
| SCHEMBL18995569 | 0.72 | PTPN1 (0.66) | PTPN1PTPN2POLBMAPTCYP2C9 | |
| SCHEMBL16622825 | 0.72 | PTPN1 (0.66) | PTPN1PTPN2POLBMAPTCYP2C9 | |
| SCHEMBL2406902 | 0.72 | POLB (1.00) | PTPN1PTPN2POLBMAPTCYP2C9 | |
| SCHEMBL31571682 | 0.72 | POLB (1.00) | PTPN1PTPN2POLBMAPTCYP2C9 | |
| SCHEMBL14769472 | 0.72 | POLB (1.00) | PTPN1PTPN2POLBMAPTCYP2C9 | |
| SCHEMBL31347993 | 0.72 | POLB (1.00) | PTPN1PTPN2POLBMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857391-A1 | LABDANE DITERPENOID COMPOUNDS, SEMEN BIOTAE EXTRACT, AND PREPARATION METHOD AND USE THEREOF | Sun Yat-Sen University (CN) | 2015-04-08 | — | — | EP | disclosed |