Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 14/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 4/20 | 0.51 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19263591 | 1.00 | FYN (0.63) | FYNDYRK1APIM1PFKFB3 | |
| SCHEMBL19263725 | 0.88 | FYN (0.51) | FYNDYRK1APIM1 | |
| SCHEMBL16491378 | 0.88 | FYN (0.51) | FYNDYRK1APIM1 | |
| SCHEMBL16491382 | 0.88 | FYN (0.51) | FYNDYRK1APIM1 | |
| SCHEMBL16491386 | 0.88 | FYN (0.51) | FYNDYRK1APIM1 | |
| SCHEMBL19263513 | 0.88 | FYN (0.51) | FYNDYRK1APIM1 | |
| SCHEMBL19263570 | 0.88 | FYN (0.51) | FYNDYRK1APIM1 | |
| SCHEMBL16491384 | 0.87 | FYN (0.51) | FYNDYRK1APIM1 | |
| SCHEMBL19263593 | 0.87 | FYN (0.51) | FYNDYRK1APIM1 | |
| SCHEMBL16491374 | 0.87 | FYN (0.52) | FYNDYRK1APIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857404-A1 | IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVE AS KINASE INHIBITOR | Daiichi Sankyo Co., Ltd. (JP) | 2015-04-08 | — | — | EP | disclosed |