Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168116 | 0.88 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL16613052 | 0.85 | PIK3CA (0.70) | PIK3CAMTOR | |
| SCHEMBL116875 | 0.82 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL3100328 | 0.79 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL168841 | 0.76 | PIK3CA (0.62) | PIK3CAMTOR | |
| SCHEMBL116964 | 0.76 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL114796 | 0.72 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL13075488 | 0.71 | PIK3CA (0.82) | PIK3CAMTOR | |
| SCHEMBL13075489 | 0.71 | PIK3CA (0.82) | PIK3CAMTOR | |
| SCHEMBL13075424 | 0.71 | PIK3CA (0.82) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424859-B1 | INHIBITORS OF PI3 KINASE AND / OR MTOR | AMGEN INC (US) | 2015-04-08 | — | — | EP | disclosed |