Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31403242 | 0.79 | IDO1 (0.55) | IDO1HSD17B10GLABRD4CREBBP | |
| SCHEMBL5437237 | 0.76 | IDO1 (0.52) | IDO1HSD17B10GLABRD4CREBBP | |
| SCHEMBL25288630 | 0.74 | HSD17B10 (0.56) | IDO1HSD17B10GLATSHRALDH1A1 | |
| SCHEMBL10738044 | 0.73 | IDO1 (0.48) | IDO1HSD17B10GLABRD4CREBBP | |
| SCHEMBL28820828 | 0.71 | IDO1 (0.47) | IDO1HSD17B10GLABRD4CREBBP | |
| SCHEMBL20751699 | 0.71 | IDO1 (0.47) | IDO1HSD17B10GLABRD4CREBBP | |
| SCHEMBL20646066 | 0.71 | IDO1 (0.47) | IDO1HSD17B10GLABRD4CREBBP | |
| SCHEMBL18101183 | 0.71 | IDO1 (0.47) | IDO1HSD17B10GLABRD4CREBBP | |
| Sulfuric Acid SCHEMBL9171022 | 0.71 | IDO1 (0.43) | IDO1HSD17B10GLABRD4CREBBP | |
| SCHEMBL5198966 | 0.71 | HSD17B10 (0.47) | IDO1HSD17B10GLATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857018-A1 | Treatment or prophylaxis of proliferative conditions | University Court of The University of Dundee (GB) | 2015-04-08 | — | — | EP | disclosed |