Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.76 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640504 | 1.00 | TRPV1 (0.76) | TRPV1NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL4878398 | 0.88 | TRPV1 (0.76) | TRPV1NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL4883678 | 0.88 | TRPV1 (0.76) | TRPV1NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL13945774 | 0.86 | NPC1 (0.69) | TRPV1NPC1RAB9AHDAC3HDAC11 | |
| SCHEMBL23657648 | 0.86 | TRPV1 (0.78) | TRPV1NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL5539768 | 0.86 | TRPV1 (0.78) | TRPV1NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL12584976 | 0.86 | EPHX2 (0.83) | TRPV1NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL22721370 | 0.85 | TRPV1 (0.76) | TRPV1NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL22815834 | 0.85 | TRPV1 (0.76) | TRPV1NPC1RAB9AHDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL5797909 | 0.85 | TRPV1 (0.76) | TRPV1NPC1RAB9AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4028387-A1 | NEW COMPOUNDS AND METHODS | BenevolentAI Bio Limited (GB) | 2022-07-20 | — | — | EP | disclosed |
| CN-104334529-B | Compounds and compositions for inhibiting the activity of ABL1, ABL2, and BCR-ABL1 | 诺华股份有限公司 | 2017-03-15 | — | — | CN | disclosed |
| EP-2338059-B1 | Ligands for aggregated tau molecules | WISTA LAB LTD (SG) | 2015-04-08 | — | — | EP | disclosed |
| CN-104334529-A | Compounds and compositions for inhibiting the activity of ABL1, ABL2, and BCR-ABL1 | NOVARTIS AG | 2015-02-04 | — | — | CN | disclosed |