Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 11/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.59 |
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26017584 | 0.92 | APP (0.76) | APPGLAGAASULT1A1SNCA | |
| SCHEMBL12422076 | 0.89 | APP (0.56) | APPGLAGAASULT1A1SNCA | |
| SCHEMBL1982196 | 0.89 | APP (0.85) | APPGLAGAASULT1A1SNCA | |
| SCHEMBL1982614 | 0.89 | APP (0.85) | APPGLAGAASULT1A1 | |
| SCHEMBL1982197 | 0.89 | APP (0.85) | APPGLAGAASULT1A1SNCA | |
| SCHEMBL1982612 | 0.89 | APP (0.85) | APPGLAGAASULT1A1 | |
| SCHEMBL1987225 | 0.87 | APP (0.53) | APPGLAGAASULT1A1SNCA | |
| SCHEMBL1987224 | 0.87 | APP (0.53) | APPGLAGAASULT1A1SNCA | |
| SCHEMBL1984302 | 0.86 | APP (0.86) | APPGLAGAASULT1A1 | |
| SCHEMBL12508994 | 0.86 | APP (0.86) | APPGLAGAASULT1A1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338059-B1 | Ligands for aggregated tau molecules | WISTA LAB LTD (SG) | 2015-04-08 | — | — | EP | disclosed |