SCHEMBL16625508

SCHEMBL16625508

Cc1c(O)c(=O)ccn1CCCCCCCCCCC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
TP53 P04637 1/20 0.52
CYP2D6 P10635 1/20 0.52
HTT P42858 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
APP P05067 1/20 0.52
HRH3 Q9Y5N1 1/20 0.52
KDM6A O15550 1/20 0.47
KDM4A O75164 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
KDM5C P41229 1/20 0.47
KDM2B Q8NHM5 1/20 0.47
DOHH Q9BU89 1/20 0.47
KDM2A Q9Y2K7 1/20 0.47
PTGS1 P23219 4/20 0.44
PTGS2 P35354 4/20 0.44
MAOB P27338 6/20 0.43
COMT P21964 1/20 0.42
FABP4 P15090 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16625509 1.00 KDM4E (0.52) KDM4ETP53CYP2D6HTTSMN1; SMN2
SCHEMBL16625510 1.00 KDM4E (0.52) KDM4ETP53CYP2D6HTTSMN1; SMN2
SCHEMBL9700234 0.94 KDM4E (0.55) KDM4ETP53CYP2D6HTTSMN1; SMN2
Hydrochloric Acid SCHEMBL9699087 0.93 KDM4E (0.54) KDM4ETP53CYP2D6HTTSMN1; SMN2
SCHEMBL9513592 0.89 APP (0.61) KDM4ETP53CYP2D6HTTSMN1; SMN2
SCHEMBL10359200 0.89 APP (0.61) KDM4ETP53CYP2D6HTTSMN1; SMN2
SCHEMBL3686713 0.88 KDM4E (0.58) KDM4ETP53CYP2D6HTTSMN1; SMN2
Hydrochloric Acid SCHEMBL8092834 0.86 KDM4E (0.56) KDM4ETP53CYP2D6HTTSMN1; SMN2
SCHEMBL9513624 0.83 APP (0.48) KDM4ETP53CYP2D6HTTSMN1; SMN2
SCHEMBL10926016 0.83 APP (0.56) KDM4ETP53CYP2D6HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150096755-A1 COMPOSITIONS COMPRISING CARBON DIOXIDE AND REVERSE MICELLES AND METHODS OF USE NEW YORK UNIVERSITY (US) 2015-04-09 US disclosed