Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CBFB | Q13951 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31199032 | 0.81 | KDM4E (0.55) | KDM4ENPC1LMNACYP1A2CCR1 | |
| SCHEMBL19961977 | 0.81 | KDM4E (0.55) | KDM4ENPC1LMNACYP1A2CCR1 | |
| SCHEMBL17570275 | 0.73 | KDM4E (0.50) | KDM4ENPC1LMNACYP1A2CCR1 | |
| SCHEMBL28320230 | 0.73 | KDM4E (0.43) | KDM4ENPC1ADORA2AADORA1LMNA | |
| SCHEMBL8962206 | 0.72 | KDM4E (0.42) | KDM4ENPC1ADORA2AADORA1LMNA | |
| SCHEMBL3884850 | 0.72 | KDM4E (0.42) | KDM4ENPC1ADORA2AADORA1LMNA | |
| SCHEMBL15883898 | 0.71 | SMN1; SMN2 (0.46) | KDM4ENPC1LMNACYP1A2CCR1 | |
| SCHEMBL30535971 | 0.70 | KDM4E (0.42) | KDM4ENPC1LMNACYP1A2CCR1 | |
| SCHEMBL4385940 | 0.70 | CYP1A2 (0.42) | KDM4ENPC1LMNACYP1A2CCR1 | |
| SCHEMBL10957813 | 0.69 | KDM4E (0.58) | KDM4ENPC1LMNACYP1A2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |