Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20393572 | 0.89 | HTT (0.43) | HTTTAS1R3TAS1R1ADRB1ADRB3 | |
| SCHEMBL16626931 | 0.88 | HTT (0.47) | HTTTAS1R3TAS1R1ADRB1ADRB3 | |
| SCHEMBL18030910 | 0.88 | HTT (0.47) | HTTTAS1R3TAS1R1ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL18010330 | 0.88 | HTT (0.46) | HTTTAS1R3TAS1R1ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL18010329 | 0.88 | HTT (0.46) | HTTTAS1R3TAS1R1ADRB1ADRB3 | |
| SCHEMBL16620250 | 0.82 | CNR1 (0.46) | HTTTAS1R3TAS1R1ADRB1ADRB3 | |
| SCHEMBL20393580 | 0.82 | HTT (0.47) | HTTTAS1R3TAS1R1ADRB1ADRB3 | |
| SCHEMBL18010313 | 0.81 | HTT (0.49) | HTTTAS1R3TAS1R1ADRB1ADRB3 | |
| SCHEMBL20798468 | 0.81 | HTT (0.47) | HTTTAS1R3TAS1R1ADRB1ADRB3 | |
| SCHEMBL16619343 | 0.81 | POLB (0.46) | HTTTAS1R3TAS1R1ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049546-A1 | INHIBITORS OF METALLO-BETA-LACTAMASE (MBL) COMPRISING A ZINC CHELATING MOIETY | UNIVERSITETET I OSLO (NO) | 2015-04-09 | — | — | WO | disclosed |