Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13555696 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL16626904 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTLIN28ATDP1KCNA5 | |
| SCHEMBL14189537 | 0.85 | CYP1A2 (0.51) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL1066335 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL3854916 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL29774122 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL26053972 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL16610081 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL16606317 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 | |
| SCHEMBL10261741 | 0.81 | CYP1A2 (0.48) | SMN1; SMN2MAPTLIN28ATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049546-A1 | INHIBITORS OF METALLO-BETA-LACTAMASE (MBL) COMPRISING A ZINC CHELATING MOIETY | UNIVERSITETET I OSLO (NO) | 2015-04-09 | — | — | WO | disclosed |