SCHEMBL16627348

SCHEMBL16627348

O=C(O)C1=NN(c2ccccc2)C(=O)/C1=C/c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.53
KMT2A Q03164 8/20 0.53
ALDH1A1 P00352 5/20 0.53
MAPT P10636 4/20 0.53
HPGD P15428 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
KAT8 Q9H7Z6 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
TDP2 O95551 1/20 0.47
MAPK1 P28482 1/20 0.47
GAA P10253 2/20 0.46
KDM4E B2RXH2 2/20 0.46
POLB P06746 1/20 0.46
RECQL P46063 1/20 0.46
GALK1 P51570 1/20 0.46
BLM P54132 1/20 0.46
THRB P10828 1/20 0.43
SAE1 Q9UBE0 1/20 0.43
UBA2 Q9UBT2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11045855 0.87 MEN1 (0.55) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL11045857 0.87 MEN1 (0.55) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL12881069 0.84 MEN1 (0.58) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL5706411 0.82 MEN1 (0.74) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL5706408 0.82 MEN1 (0.74) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL11314232 0.81 KMT2A (0.57) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL12305972 0.80 HCRTR1 (0.55) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL12880647 0.79 MAPT (0.62) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL11046387 0.77 KMT2A (0.53) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL11046384 0.77 KMT2A (0.53) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9251964-B2 Porphyrin-based compound, dye and dye-sensitized solar cell comprising the same DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-02-02 US disclosed
US-20150096618-A1 PORPHYRIN-BASED COMPOUND, DYE AND DYE-SENSITIZED SOLAR CELL COMPRISING THE SAME DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-04-09 US disclosed