Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | WEE1 | P30291 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 5/20 | 0.41 |
| ▸ | TEK | Q02763 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MYLK | Q15746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637361 | 0.97 | TP53 (0.64) | TP53WEE1CNR2KDRTEK | |
| SCHEMBL16454384 | 0.93 | TP53 (0.66) | TP53WEE1CNR2KDRTEK | |
| SCHEMBL16454764 | 0.91 | TP53 (0.61) | TP53CNR2KDRTEKNPC1 | |
| SCHEMBL15848975 | 0.89 | TP53 (0.66) | TP53CNR2KDRTEKNPC1 | |
| SCHEMBL16625998 | 0.88 | TP53 (0.62) | TP53WEE1CNR2KDRTEK | |
| SCHEMBL16120082 | 0.88 | TP53 (0.67) | TP53CNR2KDRTEKNPC1 | |
| SCHEMBL16454755 | 0.87 | TP53 (0.60) | TP53WEE1CNR2KDRTEK | |
| SCHEMBL15848962 | 0.87 | TP53 (0.60) | TP53WEE1CNR2KDRTEK | |
| SCHEMBL16454377 | 0.87 | TP53 (0.66) | TP53CNR2KDRTEKNPC1 | |
| SCHEMBL12608671 | 0.86 | TP53 (0.51) | TP53WEE1CNR2KDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050472-A1 | FUSED INDOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-04-09 | — | — | WO | disclosed |