SCHEMBL16627959

SCHEMBL16627959

CCCCCCCCCCCC/N=C(\C)CC(C)=O

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.64
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CES2 O00748 8/20 0.44
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
SIGMAR1 Q99720 2/20 0.40
EPHX1 P07099 4/20 0.39
NAAA Q02083 1/20 0.39
CES1 P23141 3/20 0.38
FAAH O00519 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16628004 1.00 HTT (0.64) HTTMEN1KMT2ACES2PRSS1
SCHEMBL21192647 1.00 HTT (0.64) HTTMEN1KMT2ACES2PRSS1
SCHEMBL16627948 1.00 HTT (0.64) HTTMEN1KMT2ACES2PRSS1
SCHEMBL21192644 1.00 HTT (0.64) HTTMEN1KMT2ACES2PRSS1
SCHEMBL21192635 1.00 HTT (0.64) HTTMEN1KMT2ACES2PRSS1
SCHEMBL21192597 0.98 HTT (0.67) HTTMEN1KMT2ACES2PRSS1
SCHEMBL21192596 0.98 HTT (0.67) HTTMEN1KMT2ACES2PRSS1
SCHEMBL21192702 0.91 HTT (0.70) HTTMEN1KMT2ACES2SIGMAR1
SCHEMBL16627953 0.91 HTT (0.70) HTTMEN1KMT2ACES2SIGMAR1
SCHEMBL9196466 0.86 KMT2A (0.47) HTTMEN1KMT2APRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
WO-2015050583-A1 METAL CONTAINING CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2015-04-09 WO disclosed