Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627917 | 0.89 | KMT2A (0.59) | NPC1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL10609912 | 0.87 | KMT2A (0.65) | NPC1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL12013645 | 0.87 | KMT2A (0.65) | NPC1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL13013116 | 0.87 | KMT2A (0.65) | NPC1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL10609916 | 0.87 | KMT2A (0.65) | NPC1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL17089330 | 0.81 | KMT2A (0.59) | NPC1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL14853282 | 0.81 | SMN1; SMN2 (0.55) | NPC1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL17089328 | 0.80 | KMT2A (0.57) | NPC1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL21368434 | 0.80 | KMT2A (0.57) | NPC1KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL13114661 | 0.80 | KMT2A (0.57) | NPC1KMT2AMEN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469799-B2 | Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2016-10-18 | — | — | US | disclosed |
| US-9469799-B2 | Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2016-10-18 | — | — | US | disclosed |
| US-20150337190-A1 | Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2015-11-26 | — | — | US | disclosed |
| US-20150337190-A1 | Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2015-11-26 | — | — | US | disclosed |
| US-9139699-B2 | Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2015-09-22 | — | — | US | disclosed |
| US-9139699-B2 | Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2015-09-22 | — | — | US | disclosed |
| WO-2015050583-A1 | METAL CONTAINING CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2015-04-09 | — | — | WO | disclosed |