Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374909 | 0.87 | MAPT (0.77) | MAPTGAAPOLBCA1CA2 | |
| SCHEMBL3840674 | 0.85 | POLB (0.51) | MAPTGAAPOLBPBRM1ALDH1A1 | |
| SCHEMBL7455315 | 0.84 | AKR1C3 (0.59) | MAPTGAAPOLBPBRM1ALDH1A1 | |
| SCHEMBL3841059 | 0.82 | ATM (0.55) | MAPTGAAPOLBPBRM1ALDH1A1 | |
| SCHEMBL9403450 | 0.82 | MAPT (0.69) | MAPTGAAPOLBCA1CA2 | |
| SCHEMBL29436991 | 0.82 | MAPT (0.69) | MAPTGAAPOLBCA1CA2 | |
| SCHEMBL8080314 | 0.81 | MAPT (0.67) | MAPTGAAPOLBCA1CA2 | |
| SCHEMBL27300542 | 0.81 | MAPT (0.67) | MAPTGAAPOLBCA1CA2 | |
| SCHEMBL10396941 | 0.80 | MAPT (0.71) | MAPTGAAPOLBCA1CA2 | |
| SCHEMBL10372151 | 0.79 | POLB (0.68) | MAPTGAAPOLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050871-A2 | ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |