Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.41 |
| ▸ | NPY1R | P25929 | 8/20 | 0.41 |
| ▸ | NPY2R | P49146 | 6/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | TFPI | P10646 | 1/20 | 0.37 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874391 | 0.91 | NPY4R (0.39) | NPY4RNPY5RNPY1RNPY2RNMT2 | |
| SCHEMBL29720839 | 0.90 | FOLH1 (0.46) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL31691754 | 0.89 | NPY4R (0.42) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL30372208 | 0.89 | NPY4R (0.42) | NPY4RNPY5RNPY1RNPY2RSIRT5 | |
| SCHEMBL31430114 | 0.89 | TFPI (0.41) | NPY4RNPY5RNPY1RNPY2RTFPI | |
| SCHEMBL31670642 | 0.88 | GNPAT (0.41) | NPY4RNPY5RNPY1RNPY2RTFPI | |
| SCHEMBL5954243 | 0.88 | QRFPR (0.42) | NPY4RNPY5RNPY1RNPY2RTFPI | |
| SCHEMBL5954239 | 0.88 | QRFPR (0.42) | NPY4RNPY5RNPY1RNPY2RTFPI | |
| SCHEMBL29591757 | 0.87 | QRFPR (0.44) | NPY4RNPY5RNPY1RNPY2RTFPI | |
| SCHEMBL29630767 | 0.87 | NPY4R (0.39) | NPY4RNPY5RNPY1RNPY2RSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051052-A2 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2015-04-09 | — | — | WO | disclosed |