Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 18/20 | 0.43 |
| ▸ | KDM6B | O15054 | 6/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18857778 | 0.84 | KDM4C (0.46) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL12097980 | 0.82 | KDM4C (0.43) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL12097414 | 0.82 | MEN1 (0.40) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL18857773 | 0.79 | KDM4C (0.46) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL5827069 | 0.77 | KDM4C (0.46) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL18857775 | 0.76 | KDM4C (0.49) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL12496875 | 0.76 | KDM4C (0.47) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL15597302 | 0.72 | KDM4C (0.50) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL15600006 | 0.72 | KDM4C (0.50) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL29870952 | 0.71 | KDM4C (0.43) | KDM4CKDM6BKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681194-B1 | 3-AMINO-PYRIDINES AS GPBAR1 AGONISTS | HOFFMANN LA ROCHE (CH) | 2015-04-15 | — | — | EP | disclosed |