Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.81 |
| ▸ | HCRTR2 | O43614 | 20/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118510 | 1.00 | HCRTR1 (0.81) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2610541 | 0.90 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2118478 | 0.89 | HCRTR1 (0.77) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2116797 | 0.89 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2610507 | 0.89 | HCRTR1 (0.77) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2119271 | 0.87 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2610496 | 0.86 | HCRTR1 (0.79) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2117836 | 0.86 | HCRTR1 (0.82) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2610523 | 0.86 | HCRTR1 (0.80) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2116351 | 0.85 | HCRTR1 (1.00) | HCRTR1HCRTR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2626350-B1 | CYCLOPROPANE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2015-04-15 | — | — | EP | disclosed |