Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16628781 | 0.92 | KLKB1 (0.77) | KLKB1 | |
| SCHEMBL554009 | 0.82 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL553005 | 0.78 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL16628807 | 0.78 | KLKB1 (0.72) | KLKB1 | |
| SCHEMBL16628782 | 0.76 | KLKB1 (0.75) | KLKB1 | |
| SCHEMBL553987 | 0.75 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL553941 | 0.74 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL554413 | 0.73 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL554350 | 0.73 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL553934 | 0.72 | KLKB1 (1.00) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601189-B1 | N-((6-AMINO-PYRIDIN-3-YL)METHYL)-HETEROARYL-CARBOXAMIDES AS INHIBITORS OF PLASMA KALLIKREIN | NOVARTIS AG (CH) | 2015-04-15 | — | — | EP | claimed |