Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455212 | 0.83 | — | — | |
| SCHEMBL311220 | 0.75 | — | — | |
| SCHEMBL982731 | 0.75 | — | — | |
| SCHEMBL495851 | 0.74 | TSHR (0.38) | TSHRNR5A1MEN1THRBHTT | |
| SCHEMBL11038938 | 0.74 | TSHR (0.38) | TSHRNR5A1MEN1THRBHTT | |
| Hexane SCHEMBL28463656 | 0.74 | TSHR (0.58) | TSHRALDH1A1THRB | |
| Ammonia Solution, Strong SCHEMBL3349086 | 0.73 | — | — | |
| SCHEMBL8991650 | 0.73 | TSHR (0.46) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL826318 | 0.73 | TSHR (0.46) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL198357 | 0.73 | TSHR (0.40) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860176-B1 | HETEROCYCLIC GROUP CONTAINED AMINO-METHANOL DERIVATIVE, AND SALT, SYNTHETIC METHOD AND USE THEREOF | BEIJING FORELAND BIOPHARMA CO LTD (CN) | 2017-09-27 | — | — | EP | disclosed |
| EP-2860176-A1 | HETEROCYCLIC GROUP CONTAINED AMINO-METHANOL DERIVATIVE, AND SALT, SYNTHETIC METHOD AND USE THEREOF | Beijing Foreland Biopharma Co., Ltd. (CN) | 2015-04-15 | — | — | EP | disclosed |