Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.90 |
| ▸ | PIK3CG | P48736 | 20/20 | 0.90 |
| ▸ | PIK3R2 | O00459 | 9/20 | 0.90 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.68 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.68 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16628965 | 0.94 | PIK3CG (1.00) | PIK3CDPIK3CGPIK3R2PIK3CAPIK3CB | |
| SCHEMBL16628977 | 0.91 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R2PIK3CAPIK3CB | |
| SCHEMBL17987923 | 0.87 | PIK3CG (0.83) | PIK3CDPIK3CGPIK3R2PIK3CAPIK3CB | |
| SCHEMBL17987925 | 0.86 | PIK3CG (0.83) | PIK3CDPIK3CGPIK3R2PIK3CAPIK3CB | |
| SCHEMBL16628971 | 0.85 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3R2PIK3CAPIK3CB | |
| SCHEMBL15306912 | 0.85 | PIK3CD (0.87) | PIK3CDPIK3CGPIK3R2PIK3CAPIK3CB | |
| SCHEMBL16619187 | 0.85 | PIK3CD (0.87) | PIK3CDPIK3CGPIK3R2PIK3CAPIK3CB | |
| SCHEMBL16630042 | 0.83 | PIK3CD (0.82) | PIK3CDPIK3CGPIK3R2PIK3CAPIK3CB | |
| SCHEMBL16630196 | 0.83 | PIK3CD (0.82) | PIK3CDPIK3CGPIK3R2PIK3CAPIK3CB | |
| SCHEMBL16630449 | 0.83 | PIK3CD (0.82) | PIK3CDPIK3CGPIK3R2PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051241-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INFINITY PHARMACEUTICALS, INC. (US) | 2015-04-09 | — | — | WO | disclosed |