Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 20/20 | 0.43 |
| ▸ | PIK3R2 | O00459 | 18/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14726631 | 0.86 | PIK3CD (0.39) | PIK3CDPIK3CGPIK3R2PIK3R1 | |
| SCHEMBL17974755 | 0.85 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL15336736 | 0.85 | PIK3CD (0.41) | PIK3CDPIK3CGPIK3R2PIK3R1 | |
| SCHEMBL15336735 | 0.84 | PIK3CD (0.44) | PIK3CDPIK3CGPIK3R2PIK3R1 | |
| SCHEMBL14726625 | 0.84 | PIK3CD (0.43) | PIK3CDPIK3CGPIK3R2PIK3R1 | |
| SCHEMBL14638046 | 0.83 | PIK3CD (0.45) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL14649470 | 0.83 | PIK3CD (0.45) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL15336737 | 0.82 | PIK3CD (0.37) | PIK3CDPIK3CGPIK3R2PIK3R1 | |
| SCHEMBL14726539 | 0.82 | PIK3CD (0.37) | PIK3CDPIK3CGPIK3R2PIK3R1 | |
| SCHEMBL16629047 | 0.82 | PIK3CD (0.57) | PIK3CDPIK3CGPIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051241-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INFINITY PHARMACEUTICALS, INC. (US) | 2015-04-09 | — | — | WO | disclosed |