Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | DPYD | Q12882 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18018832 | 0.88 | PNP (0.35) | GAAATAD2PNP | |
| SCHEMBL22883825 | 0.83 | HPRT1 (0.39) | — | |
| SCHEMBL16130073 | 0.83 | HPRT1 (0.39) | — | |
| SCHEMBL16130127 | 0.83 | GAA (0.37) | GAAATAD2DPYDMAPTALDH1A1 | |
| SCHEMBL21275612 | 0.83 | GAA (0.37) | GAAATAD2DPYDMAPTALDH1A1 | |
| SCHEMBL16629496 | 0.83 | GAA (0.37) | GAAATAD2DPYDMAPTALDH1A1 | |
| SCHEMBL16098132 | 0.83 | GAA (0.37) | GAAATAD2DPYDMAPTALDH1A1 | |
| SCHEMBL16130071 | 0.78 | P2RY14 (0.31) | — | |
| SCHEMBL17484473 | 0.78 | P2RY2 (0.37) | — | |
| SCHEMBL16102809 | 0.77 | P2RY2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051169-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2015-04-09 | — | — | WO | disclosed |