Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.41 |
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20142235 | 1.00 | UPP1 (0.56) | UPP1ALDH1A1NPC1TSHRPOLB | |
| SCHEMBL22992327 | 1.00 | UPP1 (0.56) | UPP1ALDH1A1NPC1TSHRPOLB | |
| SCHEMBL20804632 | 1.00 | UPP1 (0.56) | UPP1ALDH1A1NPC1TSHRPOLB | |
| SCHEMBL20142237 | 1.00 | UPP1 (0.56) | UPP1ALDH1A1NPC1TSHRPOLB | |
| SCHEMBL7151231 | 0.92 | UPP1 (0.61) | UPP1ALDH1A1NPC1POLBGAA | |
| SCHEMBL7151233 | 0.92 | UPP1 (0.61) | UPP1ALDH1A1NPC1POLBGAA | |
| SCHEMBL7787666 | 0.92 | UPP1 (0.61) | UPP1ALDH1A1NPC1POLBGAA | |
| SCHEMBL22801918 | 0.92 | UPP1 (0.48) | UPP1ALDH1A1NPC1TSHRPOLB | |
| SCHEMBL11648434 | 0.89 | UPP1 (0.58) | UPP1ALDH1A1NPC1RNASE1 | |
| SCHEMBL11648441 | 0.89 | UPP1 (0.58) | UPP1ALDH1A1NPC1RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |