SCHEMBL1663251

SCHEMBL1663251

N[C@H]1CC[C@@H](OC=O)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1712153 1.00
SCHEMBL16240576 1.00
Hydrochloric Acid SCHEMBL10933438 0.98
SCHEMBL1527351 0.86 ROCK1 (0.33)
SCHEMBL1969711 0.86 ROCK1 (0.33)
SCHEMBL12993363 0.85
SCHEMBL384166 0.85
SCHEMBL3493287 0.85 CA1 (0.34)
Hydrochloric Acid SCHEMBL28386240 0.83
Hydrochloric Acid SCHEMBL28395463 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2491009-B1 CYCLOPENTANECARBOXAMIDE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE BOEHRINGER INGELHEIM INT (DE) 2017-07-05 EP disclosed
US-8614238-B2 Cyclopentanecarboxamide derivatives, medicaments containing such compounds and their use BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-12-24 US disclosed
US-20130053412-A1 Cyclopentanecarboxamide derivatives, medicaments containing such compounds and their use BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-02-28 US disclosed
EP-2491009-A1 CYCLOPENTANECARBOXAMIDE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE Boehringer Ingelheim International GmbH (DE) 2012-08-29 EP disclosed
WO-2011048018-A1 CYCLOPENTANECARBOXAMIDE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-04-28 WO disclosed