Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1657232 | 0.76 | GRM5 (0.60) | GRM5 | |
| SCHEMBL6310651 | 0.74 | GRM5 (0.54) | GRM5 | |
| SCHEMBL26707843 | 0.69 | PREP (0.61) | — | |
| SCHEMBL26616485 | 0.69 | PREP (0.61) | — | |
| SCHEMBL1658046 | 0.68 | SMN1; SMN2 (0.54) | GRM5 | |
| SCHEMBL26707841 | 0.68 | PREP (0.52) | — | |
| SCHEMBL17059010 | 0.66 | GRM5 (0.49) | GRM5 | |
| SCHEMBL1659943 | 0.65 | GRM5 (0.59) | GRM5 | |
| SCHEMBL1656983 | 0.65 | GRM5 (0.60) | GRM5 | |
| SCHEMBL4462960 | 0.65 | ACACB (0.50) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2490541-A1 | 2-SUBSTITUTED-ETHYNYLTHIAZOLE DERIVATIVES AND USES OF SAME | H. Lundbeck A/S (DK) | 2012-08-29 | — | — | EP | claimed |
| WO-2011050063-A1 | 2-SUBSTITUTED-ETHYNYLTHIAZOLE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2011-04-28 | — | — | WO | claimed |