Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169800 | 0.92 | PIK3CA (0.60) | PIK3CAMTOR | |
| SCHEMBL114698 | 0.85 | PIK3CA (0.81) | PIK3CAMTOR | |
| SCHEMBL115793 | 0.78 | PIK3CA (0.68) | PIK3CAMTOR | |
| SCHEMBL115796 | 0.78 | PIK3CA (0.80) | PIK3CAMTOR | |
| SCHEMBL114387 | 0.78 | PIK3CA (0.80) | PIK3CAMTOR | |
| SCHEMBL114724 | 0.77 | PIK3CA (0.81) | PIK3CAMTOR | |
| SCHEMBL116049 | 0.75 | PIK3CA (0.81) | PIK3CAMTOR | |
| SCHEMBL115451 | 0.74 | PIK3CA (0.82) | PIK3CAMTOR | |
| SCHEMBL114829 | 0.73 | PIK3CA (0.79) | PIK3CAMTOR | |
| SCHEMBL114558 | 0.73 | PIK3CA (0.80) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424859-A1 | INHIBITORS OF PI3 KINASE AND / OR MTOR | Amgen, Inc (US) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010126895-A1 | INHIBITORS OF PI3 KINASE AND / OR MTOR | AMGEN INC. (US) | 2010-11-04 | — | — | WO | disclosed |