Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634708 | 1.00 | IDO1 (0.36) | IDO1CYP1A2GAACYP2D6CYP2C9 | |
| SCHEMBL16634705 | 0.90 | IDO1 (0.37) | IDO1CYP1A2GAACYP2D6CYP2C9 | |
| SCHEMBL16634704 | 0.90 | IDO1 (0.37) | IDO1CYP1A2GAACYP2D6CYP2C9 | |
| SCHEMBL16634817 | 0.86 | IDO1 (0.38) | IDO1CYP1A2GAACYP2D6CYP2C9 | |
| SCHEMBL16634816 | 0.86 | IDO1 (0.38) | IDO1CYP1A2GAACYP2D6CYP2C9 | |
| SCHEMBL16634612 | 0.83 | IDO1 (0.39) | IDO1CYP1A2GAACYP2D6CYP2C9 | |
| SCHEMBL16634613 | 0.83 | IDO1 (0.39) | IDO1CYP1A2GAACYP2D6CYP2C9 | |
| SCHEMBL16634749 | 0.81 | IDO1 (0.40) | IDO1CYP1A2GAACYP2D6CYP2C9 | |
| SCHEMBL16634748 | 0.81 | IDO1 (0.40) | IDO1CYP1A2GAACYP2D6CYP2C9 | |
| SCHEMBL16634993 | 0.81 | IDO1 (0.41) | IDO1CYP1A2GAACYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015053576-A1 | METHOD FOR PREPARATION OF 3-ALKYLTHIO-2-BROMOPYRIDINE | LG LIFE SCIENCES LTD. (KR) | 2015-04-16 | — | — | WO | claimed |
| WO-2015053576-A1 | METHOD FOR PREPARATION OF 3-ALKYLTHIO-2-BROMOPYRIDINE | LG LIFE SCIENCES LTD. (KR) | 2015-04-16 | — | — | WO | disclosed |