Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.77 |
| ▸ | PARP2 | Q9UGN5 | 13/20 | 0.77 |
| ▸ | PARP3 | Q9Y6F1 | 13/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1422404 | 0.87 | PARP1 (1.00) | PARP1PARP2PARP3 | |
| SCHEMBL4766624 | 0.85 | PARP1 (0.71) | PARP1PARP2PARP3 | |
| Hydrochloric Acid SCHEMBL27738209 | 0.84 | PARP1 (0.94) | PARP1PARP2PARP3 | |
| SCHEMBL2264036 | 0.84 | PARP1 (0.79) | PARP1PARP2PARP3 | |
| SCHEMBL23598274 | 0.83 | PARP1 (0.77) | PARP1PARP2PARP3 | |
| SCHEMBL2264064 | 0.83 | PARP1 (1.00) | PARP1PARP2PARP3 | |
| SCHEMBL2267025 | 0.83 | PARP1 (0.77) | PARP1PARP2PARP3 | |
| Hydrochloric Acid SCHEMBL2263931 | 0.83 | PARP1 (0.77) | PARP1PARP2PARP3 | |
| SCHEMBL2263821 | 0.82 | PARP1 (0.80) | PARP1PARP2PARP3 | |
| SCHEMBL30157404 | 0.82 | PARP1 (0.76) | PARP1PARP2PARP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051766-A1 | AMIDS SUBSTITUTED INDAZOLE DERIVATIVEES AS PLOY (ADP-RIBOSE) POLYMERASE INHIBITORS | BETTA PHARMACEUTICALS CO., LTD (CN) | 2015-04-16 | — | — | WO | disclosed |