Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16635814 | 1.00 | GRM5 (1.00) | GRM5 | |
| SCHEMBL16635911 | 0.92 | GRM5 (1.00) | GRM5 | |
| SCHEMBL16635799 | 0.90 | GRM5 (1.00) | GRM5 | |
| SCHEMBL16647390 | 0.90 | GRM5 (1.00) | GRM5 | |
| SCHEMBL16635406 | 0.90 | GRM5 (1.00) | GRM5 | |
| SCHEMBL16647380 | 0.89 | GRM5 (1.00) | GRM5 | |
| SCHEMBL16647412 | 0.89 | GRM5 (1.00) | GRM5 | |
| SCHEMBL17982688 | 0.89 | GRM5 (1.00) | GRM5 | |
| SCHEMBL16647413 | 0.89 | GRM5 (1.00) | GRM5 | |
| SCHEMBL16647389 | 0.89 | GRM5 (1.00) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055306-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | Bristol-Myers Squibb Company (US) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015054103-A1 | OXAZOLIDINONES AS MODULATORS OF MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-04-16 | — | — | WO | disclosed |