SCHEMBL16636360

SCHEMBL16636360

C=CCOCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCC4 O15439 1/20 0.55
MAPT P10636 1/20 0.55
ALDH1A1 P00352 4/20 0.50
TSHR P16473 7/20 0.48
LMNA P02545 3/20 0.48
NFKB1 P19838 1/20 0.48
PMP22 Q01453 1/20 0.48
GPR84 Q9NQS5 6/20 0.41
FFAR1 O14842 2/20 0.41
FFAR4 Q5NUL3 2/20 0.41
PPARG P37231 6/20 0.40
PPARD Q03181 6/20 0.40
PPARA Q07869 6/20 0.40
HDAC11 Q96DB2 5/20 0.40
TLR2 O60603 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 2/20 0.40
FABP4 P15090 2/20 0.40
ALOX15 P16050 2/20 0.40
PTPN1 P18031 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28559661 1.00 ABCC4 (0.55) ABCC4MAPTALDH1A1TSHRLMNA
SCHEMBL8215072 1.00 ABCC4 (0.55) ABCC4MAPTALDH1A1TSHRLMNA
SCHEMBL25756048 1.00 ABCC4 (0.55) ABCC4MAPTALDH1A1TSHRLMNA
SCHEMBL1967454 0.98 ABCC4 (0.52) ABCC4MAPTALDH1A1TSHRLMNA
SCHEMBL3935151 0.92 TSHR (0.48) ABCC4MAPTALDH1A1TSHRLMNA
Adipic Acid SCHEMBL7135978 0.87 ABCC4 (0.58) ABCC4MAPTALDH1A1TSHRLMNA
Adipic Acid SCHEMBL3224275 0.86 ABCC4 (0.48) ABCC4MAPTALDH1A1TSHRLMNA
SCHEMBL8069530 0.84 TSHR (0.42) ABCC4MAPTALDH1A1TSHRLMNA
SCHEMBL19743043 0.83 MEN1 (0.36) ABCC4MAPTALDH1A1TSHRLMNA
SCHEMBL222657 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105814127-B Reactive functional group silicone composition 迈图高新材料股份有限公司 2019-07-26 CN disclosed
EP-3036279-B1 REACTIVE FUNCTIONAL SILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MAT GMBH (DE) 2019-05-08 EP disclosed
US-9771458-B2 Reactive functional siloxane compositions MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2017-09-26 US disclosed
US-20160251483-A1 Reactive Functional Siloxane Compositions MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2016-09-01 US disclosed
CN-105814127-A Reactive functional siloxane compositions 迈图高新材料股份有限公司 2016-07-27 CN disclosed
EP-3036279-A1 REACTIVE FUNCTIONAL SILOXANE COMPOSITIONS Momentive Performance Materials GmbH (DE) 2016-06-29 EP disclosed
WO-2015052229-A1 REACTIVE FUNCTIONAL SILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2015-04-16 WO disclosed