Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661773 | 0.87 | S1PR1 (0.51) | S1PR1S1PR3 | |
| SCHEMBL1663693 | 0.86 | S1PR1 (0.61) | S1PR1S1PR3 | |
| SCHEMBL1661178 | 0.83 | S1PR1 (0.56) | S1PR1S1PR3 | |
| SCHEMBL1602920 | 0.79 | S1PR1 (0.62) | S1PR1S1PR3 | |
| SCHEMBL1661770 | 0.78 | S1PR1 (0.62) | S1PR1S1PR3 | |
| SCHEMBL1661439 | 0.75 | S1PR1 (0.81) | S1PR1S1PR3 | |
| SCHEMBL1661282 | 0.74 | S1PR1 (0.46) | S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL1661541 | 0.74 | S1PR1 (0.80) | S1PR1S1PR3 | |
| SCHEMBL1661175 | 0.74 | S1PR1 (0.78) | S1PR1S1PR3 | |
| SCHEMBL1662175 | 0.73 | S1PR1 (0.55) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306994-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | Amgen, Inc (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009154775-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC. (US) | 2009-12-23 | — | — | WO | disclosed |