Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10715636 | 0.82 | TSHR (0.53) | LMNATSHRNPC1RAB9AHTT | |
| SCHEMBL6260059 | 0.78 | TSHR (0.57) | LMNATSHRNPC1RAB9AHTT | |
| SCHEMBL13625602 | 0.75 | TSHR (0.63) | LMNATSHRNPC1RAB9AHTT | |
| Benzoic Acid 1-Methylethyl Ester SCHEMBL96918 | 0.75 | PDCD1 (0.78) | LMNATSHRNPC1RAB9AHTT | |
| SCHEMBL25846716 | 0.75 | TSHR (0.63) | LMNATSHRNPC1RAB9AHTT | |
| SCHEMBL13700339 | 0.75 | TSHR (0.63) | LMNATSHRNPC1RAB9AHTT | |
| SCHEMBL29311500 | 0.75 | TSHR (0.63) | LMNATSHRNPC1RAB9AHTT | |
| SCHEMBL10239104 | 0.75 | TSHR (0.63) | LMNATSHRNPC1RAB9AHTT | |
| SCHEMBL6660758 | 0.75 | TSHR (0.63) | LMNATSHRNPC1RAB9AHTT | |
| SCHEMBL1786752 | 0.75 | TSHR (0.63) | LMNATSHRNPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055293-A1 | DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS | Fondazione Istituto Italiano di Tecnologia (IT) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015052283-A1 | DIARYLALKYLAMINE REV-ERB ANTAGONISTS AND THEIR USE AS MEDICAMENTS | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-04-16 | — | — | WO | disclosed |
| CN-1903862-B | Substituted methanoyl alkyl phosphonate ester kind optical active isomer possessing herbicide activity and its preparation method | UNIV HUAZHONG NORMAL | 2012-10-10 | — | — | CN | disclosed |
| CN-1903862-A | Substituted methanoyl alkyl phosphonate ester kind optical active isomer possessing herbiciding activity and its preparation method | UNIV HUAZHONG (CN) | 2007-01-31 | — | — | CN | disclosed |