SCHEMBL16637005

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29765786	1.00	KIT (0.63)	KITCNR1CNR2PDGFRBGBA1
	SCHEMBL16647248	0.96	KIT (0.63)	KITCNR1CNR2PDGFRBGBA1
	SCHEMBL16637099	0.92	KIT (0.53)	KITCNR1CNR2PDGFRBKRAS
	SCHEMBL29765709	0.92	KIT (0.53)	KITCNR1CNR2PDGFRBKRAS
	SCHEMBL16636967	0.90	CNR1 (0.57)	KITCNR1CNR2PDGFRBKRAS
	SCHEMBL16637970	0.86	PDGFRB (0.51)	KITPDGFRBKRASUSP2ALDH1A1
	SCHEMBL17030841	0.84	KIT (0.53)	KITCNR1CNR2PDGFRBKRAS
	SCHEMBL16637110	0.83	KIT (0.52)	KITCNR1CNR2PDGFRBTLR9
	SCHEMBL30902163	0.83	KIT (0.52)	KITCNR1CNR2PDGFRBTLR9
	SCHEMBL2916238	0.83	KIT (0.62)	KITCNR1CNR2PDGFRBGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.