Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 12/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663193 | 0.87 | GRM5 (0.45) | GRM5APPFFAR1FFAR4EGLN1 | |
| SCHEMBL1657995 | 0.80 | GRM5 (0.45) | GRM5APP | |
| SCHEMBL1663205 | 0.80 | GRM5 (0.44) | GRM5APPFFAR1FFAR4EGLN1 | |
| SCHEMBL15226559 | 0.79 | KMT2A (0.43) | GRM5APPFFAR1 | |
| SCHEMBL1658030 | 0.77 | GRM5 (0.40) | GRM5APP | |
| SCHEMBL1659965 | 0.76 | GRM5 (0.50) | GRM5 | |
| SCHEMBL1657728 | 0.76 | GRM5 (0.53) | GRM5 | |
| SCHEMBL1657724 | 0.75 | GRM5 (0.55) | GRM5 | |
| SCHEMBL1658413 | 0.74 | GRM5 (0.46) | GRM5 | |
| SCHEMBL1658169 | 0.74 | SMN1; SMN2 (0.52) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2490541-A1 | 2-SUBSTITUTED-ETHYNYLTHIAZOLE DERIVATIVES AND USES OF SAME | H. Lundbeck A/S (DK) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011050063-A1 | 2-SUBSTITUTED-ETHYNYLTHIAZOLE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2011-04-28 | — | — | WO | disclosed |