SCHEMBL16637474

SCHEMBL16637474

C=CCC1(O)COC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL1533018 0.97
SCHEMBL1379102 0.90
SCHEMBL17162693 0.75
SCHEMBL31085444 0.75 TSHR (0.32)
SCHEMBL1124085 0.75
SCHEMBL14126181 0.74
SCHEMBL45544 0.73
SCHEMBL2106334 0.72 PDE9A (0.32)
Oxirane SCHEMBL7156599 0.72 MEN1 (0.31)
SCHEMBL252753 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735449-A1 TETRACYCLIC COMPOUNDS CONTAINING A FUSED INDOLE FOR TREATING APOL1-MEDIATED CHRONIC KIDNEY DISEASE OmniAB, Inc. (US) 2026-05-06 EP disclosed
WO-2025006262-A1 TETRACYCLIC COMPOUNDS CONTAINING A FUSED INDOLE FOR TREATING APOL1-MEDIATED CHRONIC KIDNEY DISEASE OMNIAB, INC. (US) 2025-01-02 WO disclosed
CN-116120295-A N-substituted imidazole formate derivative and application thereof 成都麻沸散医药科技有限公司 2023-05-16 CN disclosed
US-11464790-B2 Triterpenoids with HIV maturation inhibitory activity ViiV Healthcare UK (No.4) Limited (GB) 2022-10-11 US disclosed
US-11434205-B2 Substituted imidazole carboxylate derivatives and the use thereof CHENGDU MFS PHARMA. CO., LTD. (CN) 2022-09-06 US disclosed
CN-108602778-B 8-amino-2-oxo-1, 3-diaza-spiro- [4.5] -decane derivatives 格吕伦塔尔有限公司 2021-12-10 CN disclosed
US-20210179595-A1 8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives Grünenthal GmbH (DE) 2021-06-17 US disclosed
US-20200399255-A1 8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives Grünenthal GmbH (DE) 2020-12-24 US disclosed
EP-3750910-A1 TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY VIIV Healthcare UK(No.4) Limited (GB) 2020-12-16 EP disclosed
EP-3055288-B1 ANTIDIABETIC TRICYCLIC COMPOUNDS MERCK SHARP & DOHME (US) 2020-12-16 EP disclosed
WO-2016112088-A1 ARYLOXYACETYLINDOLES AND ANALOGS AS ANTIBIOTIC TOLERANCE INHIBITORS SPERO THERAPEUTICS, INC. (US) 2016-07-14 WO disclosed
US-20150291655-A1 TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) 2015-10-15 US disclosed
WO-2015157483-A1 TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY, SUBSTITUTED IN POSITION 3 BY A NON-AROMATIC RING CARRYING A HALOALKYL SUBSTITUENT BRISTOL-MYERS SQUIBB COMPANY (US) 2015-10-15 WO disclosed
US-20150291655-A1 TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) 2015-10-15 US disclosed
WO-2015157483-A1 TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY, SUBSTITUTED IN POSITION 3 BY A NON-AROMATIC RING CARRYING A HALOALKYL SUBSTITUENT BRISTOL-MYERS SQUIBB COMPANY (US) 2015-10-15 WO disclosed
US-20150291655-A1 TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY VIIV HEALTHCARE UK (NO. 4) LIMITED (GB) 2015-10-15 US disclosed
WO-2015051496-A1 ANTIDIABETIC TRICYCLIC COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2015-04-16 WO disclosed
WO-2015051725-A1 ANTIDIABETIC TRICYCLIC COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2015-04-16 WO disclosed
WO-2015051496-A1 ANTIDIABETIC TRICYCLIC COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2015-04-16 WO disclosed
WO-2015051725-A1 ANTIDIABETIC TRICYCLIC COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2015-04-16 WO disclosed