Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 5/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16637561 | 0.86 | LCAT (0.32) | LRRK2AR | |
| SCHEMBL18070192 | 0.84 | AR (0.32) | LRRK2AR | |
| SCHEMBL16647382 | 0.84 | PIK3CD (0.31) | — | |
| SCHEMBL16647306 | 0.84 | CYP17A1 (0.37) | GRM2HTR2AHTR2CARCYP1A2 | |
| SCHEMBL16647272 | 0.84 | HDAC3 (0.33) | HDAC3HDAC1HDAC2HDAC6HCRTR1 | |
| SCHEMBL16647321 | 0.83 | COMT (0.37) | LRRK2AR | |
| SCHEMBL16647343 | 0.83 | PIK3CA (0.33) | HCRTR1 | |
| SCHEMBL16647342 | 0.81 | PIK3CA (0.37) | — | |
| SCHEMBL16647287 | 0.81 | CLK2 (0.31) | LRRK2AR | |
| SCHEMBL16647341 | 0.80 | CYP11B1 (0.39) | CYP1A2WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11608323-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2023-03-21 | — | — | US | disclosed |
| EP-3054773-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-26 | — | — | EP | disclosed |
| EP-3054773-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-26 | — | — | EP | disclosed |
| CN-111961033-A | Herbicidal compounds | 先正达参股股份有限公司 | 2020-11-20 | — | — | CN | disclosed |
| US-20190112288-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-18 | — | — | US | disclosed |
| US-20190112288-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-18 | — | — | US | disclosed |
| US-20160264547-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | US | disclosed |
| US-20160264547-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | US | disclosed |
| US-20160264547-A1 | Herbicidal Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-09-15 | — | — | US | disclosed |
| EP-3054773-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015052076-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-16 | — | — | WO | disclosed |
| WO-2015052076-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190112288-A1 | HERBICIDAL COMPOUNDS | DDT, RDX, CBR3 | HDAC3 1739/4885HDAC1 1353/4885HDAC2 2727/4885 |
| US-20160264547-A1 | Herbicidal Compounds | DDT, RDX, CBR3 | HDAC3 1758/4885HDAC1 1451/4885HDAC2 2729/4885 |
| US-11608323-B2 | Herbicidal compounds | DDT, RDX, CBR3 | HDAC3 1739/4885HDAC1 1353/4885HDAC2 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.